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- The VES College of Law is an institution par excellence equipped with qualified full time teaching faculties focusing not only on the development of the skills within the students but also on to develop mediation skills within the students.
- The VES College of Pharmacy was started in July 2007. Our goal is to impart Quality Education and contribute towards character building of students. Our endeavor is to provide a conducive academic atmosphere for students to freely interact for better learning.
Recent Submissions
Item type:Publication, Synthesis of Cholest-5-en-3-ol(3β)-3-[4-(2,2,2-trifluoroacetamido) benzoate] (ChTfAB) a Thermotropic Liquid Crystalline Material(Indian Journal of Chemical, 2023) Navale, Dinesh; Ranade, PrasannaThe synthesis of cholest-5-en-3-ol(3β)-3-[4-(2,2,2-trifluoroacetamido)benzoate] (ChTfAB) is carried out by esterification of cholesterol and p-nitrobenzoic acid using DCC, DMAP, followed by reduction of nitro group using SnCl2. The so formed amino group is further N-acylated using trifluoroacetic anhydride. The newly synthesized compound is characterized using IR and 1H NMR spectroscopic techniques. Its mesomorphic properties have been investigated using Differential Scanning Colorimetry (DSC) and Polarising Optical Microscopy (POM). The thermal and phase behaviour studies reveal the synthesized compound to be an enantiotropic, thermotropic liquid crystal. This synthesized compound overcomes the problem of degrading at the melting temperature associated with one of the previously synthesized and reported steroidal compound.Item type:Publication, Synthesis of Fluorinated Ferrocene Derivatives for their Thermal Behavior and their In Silico studies in Designing of Potential Breast Cancer Inhibitors(Indian Journal of Chemistry, 2024) Navale, Dinesh; Ranade, PrasannaThe docking studies of the different fluorinated ferrocene derivatives have been carried out against estrogen receptor enzymes. The docking results are very much comparable with standard drug tamoxifen. The designed fluorinated ferrocene derivatives show similarity in binding as tamoxifen exhibits estrogen receptor enzymes in silico. Docking studies reveal that designed fluorinated ferrocene derivatives have potential against breast cancer in silico. The ADME properties of some of the designed compounds are indicative of the drug likeness of compounds. All the designed fluorinated derivatives have been synthesized and have been evaluated for their thermal behavior.Item type:Item, Digital Health Platforms – Impact on Patient-Centric Care(Zendo, 2025-10-17) Barve, Pratik Vasant; Badhe, PravinItem type:Publication, In Silico Study of 4-Amino Substituted-7-Chloroquinoline Derivatives as Plasmodium Falciparum Lactate Dehydrogenase Inhibitors(Indian Journal of Biochemistry and Biophysics, 2024) Ranade, Prasanna; Navale, DineshThe docking between 4-amino substituted-7-chloroquinoline derivatives and Plasmodium falciparum lactate dehydrogenase were carried out. The designed 4-aminosubstitued-7-chloroquinoline derivatives show comparable dock score with chloroquine. The docking study reveals that the binding of 4-amino substituted-7-chloroquinoline derivatives and amino acids in the binding pocket of Plasmodium falciparum lactate dehydrogenase is observed. Predicted ADME properties of designed compounds are in range.Item type:Publication, Extractive Spectrophotometric Determination of Copper (II) with [N-(O-Methoxy Benzaldehyde)- 2-Amino Phenol](International Journal of Chemical Science, 2013) Makhijan, Ritika; Barhate, VasantA simple, rapid and sensitive spectrophotometric method has been developed for the determination of Cu (II) by using N-(o-methoxy benzaldehyde) 2-aminophenol (NOMBAP) as an analytical reagent. NOMBAP has been synthesized and characterized by elemental and spectral analysis. NOMBAP extracts Cu (II) quantitatively (99.78%) into chloroform from an aqueous solution of pH range 5.7-6.8. The chloroform extract shows an intense peak at 440 nm (λmax). Beer’s law is obeyed over the Cu (II) concentration range of 0.1-4.0 µg/mL. The Sandell’s sensitivity and molar absorptivity for Cu-NOMBAP system is 0.00246 μgcm-2 and 25739 L mole-1 cm-1, respectively. The composition of extracted species is found to be 1 : 2 (Cu: NOMBAP) by Job’s Continuous Variation and Mole Ratio Method. The average of 10 determination of 10 µg of Cu (II) in 10 cm3 of solution is 10.02 µg, which is varied between 9.964 µg and 10.076 µg at 95% confidence limit and standard deviation is ± 0.079. Interference by various ions has been studied. The proposed method has been successfully applied for determination of Cu (II) in alloy and pharmaceutical samples.